Ken Murphy et al.《janeway's immunobiology(8th)》:Garland Scie
今天要介绍的这篇文献讲的就是“表达自体抗原”的肿瘤细胞如何影响专职抗原递呈细胞(肿瘤相关巨噬细胞,TAM)导致CD8+T细胞耗竭,实现免疫逃逸的故事,题为“Tumor-associated macrophages expressing the transcription factor IRF8 promote T cell exhaustion in cancer”发表在免疫学权威顶刊《Immunity》上。(IF=43.474)